Promotion effects of optical antipodes on the formation of helical fibrils: chiral perfluorinated gelators.
نویسندگان
چکیده
A chiral gelator, RR- or SS-N,N'-diperfluorooctanoyl-1,2-diaminocyclohexane, gelated racemic 2-butanol. The gel was most stable at the racemic mixture, its stability lowered with the increase in the optical purity of the gelator. Notably, characteristic helically coiled fibrils were formed in the narrow region of enantiomer excess (ee = 0.2-0.4). Promotion effects of the antipodal enantiomers are proposed.
منابع مشابه
Molecular origin for helical winding of fibrils formed by perfluorinated gelators.
A chiral low-molecular weight gelator, N,N'-diperfluoroheptanoyl-1,2(R,R)- or -1,2(S,S)-diaminocyclohexane, was prepared to form a gel of acetonitrile. The conformation of the gelator in fibrils was determined by vibrational circular dichroism spectra, providing a molecular model for self-assembly in a helical fibril.
متن کاملTheoretical study of magnetic susceptibility and optical activity of small molecules containing one chiral center
In the first part of this work, correlation between optical activity and elements of magnetic susceptibility tensor (MST) for five classes of model small molecules containing a single chiral center has been studied using quantum computational techniques at DFT-B3LYP level of theory with 6-311G basis set. Several molecular properties are used to reduce the MST elements prior to the examination o...
متن کاملGelation of perfluorinated liquids by N-alkyl perfluoroalkanamides.
Gels comprised of low-molecular-mass organic gelators (LMOGs), N-alkyl perfluoroalkanamides [F(CF2)(m)CONH(CH2)(n)H; FmNHn], and several perfluorinated liquids are described. The gelation ability of the amides has been compared to that of two analogous alkyl perfluoroalkanoates. The properties of these gels have been correlated with the N-alkyl and (to a lesser extent) perfluoroalkyl chain leng...
متن کاملAnti-amyloidogenic and disaggregating effects of Salvia officinalis in vitro: a strategy to reduce the insulin amyloid fibrils due to repeated subcutaneous injections in diabetic patients
Background: Recently, there has been growing efforts to elucidate the molecular mechanism of amyloid formation and investigating effective compounds for inhibiting of amyloid structures. Investigation of the fibrillation process through its induction and inhibition using specific compounds such as aromatic derivatives provide useful information for stabilizing the protein structure. In the pres...
متن کاملModelling Dispersion Characteristics of Circular Optical Waveguide with Helical Winding– Comparison for Different Pitch Angles
In this Article dispersion characteristic of conventional optical waveguide with helical winding at core – cladding interface has been obtained. The model dispersion characteristics of optical waveguide with helical winding at core-cladding interface have been obtained for five different pitch angles. This paper includes dispersion characteristics of optical waveguide with helical winding, and ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 48 32 شماره
صفحات -
تاریخ انتشار 2012